| Round | Overall | Player |
|---|---|---|
| 1 | 7th | OF Joey Gallo Tex |
| 2 | 18th | SP Walker Buehler LAD |
| 3 | 31st | SP Justin Verlander Hou |
| 4 | 42nd | 3B Yoan Moncada ChA |
| 5 | 55th | SP Mike Clevinger SD |
| 6 | 66th | 1B Rhys Hoskins Phi |
| 7 | 79th | SP Luis Castillo Cin |
| 8 | 90th | 2B Cavan Biggio Tor |
| 9 | 103rd | SP Frankie Montas Oak |
| 10 | 114th | DH Edwin Encarnacion ChA |
| 11 | 127th | OF Whit Merrifield KC |
| 12 | 138th | SP Carlos Carrasco Cle |
| 13 | 151st | SS Paul DeJong StL |
| 14 | 162nd | SS Dansby Swanson Atl |
| 15 | 175th | 3B Scott Kingery Phi |
| 16 | 186th | RP Carlos Martinez StL |
| 17 | 199th | RP Brandon Workman Bos |
| 18 | 210th | C Tom Murphy Sea |
| 19 | 223rd | SP Matt Shoemaker Tor |
| 20 | 234th | 3B Yandy Diaz TB |
| 21 | 247th | OF J.D. Davis NYN |
| 22 | 258th | RP Giovanny Gallegos StL |
| 23 | 271st | OF Yoshitomo Tsutsugo TB |
| 24 | 282nd | OF Mitch Haniger Sea |
| 25 | 295th | SP Reynaldo Lopez ChA |
| 26 | 306th | OF Brian Anderson Mia |
| 27 | 319th | OF Avisail Garcia Mil |
| 28 | 330th | RP Yoshihisa Hirano Sea |
| 29 | 343rd | C Isiah Kiner-Falefa Tex |