| Round | Overall | Player |
|---|---|---|
| 1 | 12th | 1B Pete Alonso NYN |
| 2 | 13th | SP Gerrit Cole NYA |
| 3 | 36th | 3B Vladimir Guerrero Jr. Tor |
| 4 | 37th | OF Giancarlo Stanton NYA |
| 5 | 60th | 1B Max Muncy LAD |
| 6 | 61st | SP Clayton Kershaw LAD |
| 7 | 84th | 2B Mike Moustakas Cin |
| 8 | 85th | RP Aroldis Chapman NYA |
| 9 | 108th | RP Brad Hand Cle |
| 10 | 109th | 3B Eduardo Escobar Ari |
| 11 | 132nd | OF Justin Upton LAA |
| 12 | 133rd | SS Jorge Polanco Min |
| 13 | 156th | DH Khris Davis Oak |
| 14 | 157th | SP Dakota Hudson StL |
| 15 | 180th | OF Nomar Mazara ChA |
| 16 | 181st | RP Ken Giles Tor |
| 17 | 204th | OF Kyle Tucker Hou |
| 18 | 205th | 1B Dan Vogelbach Sea |
| 19 | 228th | 1B Justin Smoak Ret |
| 20 | 229th | SS Luis Urias Mil |
| 21 | 252nd | OF Sam Hilliard Col |
| 22 | 253rd | SP Steven Matz NYN |
| 23 | 276th | SP Anthony DeSclafani Cin |
| 24 | 277th | 2B Cesar Hernández Cle |
| 25 | 300th | OF Brett Gardner NYA |
| 26 | 301st | SP Michael Pineda Min |
| 27 | 324th | SP Dustin May LAD |
| 28 | 325th | C Jason Castro SD |
| 29 | 348th | C Roberto Perez Cle |