| Round | Overall | Player |
|---|---|---|
| 1 | 4th | OF Mookie Betts LAD |
| 2 | 21st | OF George Springer Hou |
| 3 | 28th | 1B Anthony Rizzo ChN |
| 4 | 45th | SS Trea Turner Was |
| 5 | 52nd | SP Aaron Nola Phi |
| 6 | 69th | OF Starling Marte Ari |
| 7 | 76th | OF Austin Meadows TB |
| 8 | 93rd | C Yasmani Grandal ChA |
| 9 | 100th | SP Charlie Morton TB |
| 10 | 117th | 3B Jeff McNeil NYN |
| 11 | 124th | SP Sean Manaea Oak |
| 12 | 141st | SP Hyun-Jin Ryu Tor |
| 13 | 148th | SP Mike Minor Oak |
| 14 | 165th | 2B Brandon Lowe TB |
| 15 | 172nd | OF Victor Robles Was |
| 16 | 189th | RP Raisel Iglesias LAA |
| 17 | 196th | RP Hansel Robles Min |
| 18 | 213th | SP Michael Kopech ChA |
| 19 | 220th | RP Mark Melancon Atl |
| 20 | 237th | SS Amed Rosario NYN |
| 21 | 244th | C Danny Jansen Tor |
| 22 | 261st | 3B Austin Riley Atl |
| 23 | 268th | 2B Luis Arraez Min |
| 24 | 285th | SP Alex Wood LAD |
| 25 | 292nd | SP Kwang-Hyun Kim StL |
| 26 | 309th | OF Aristides Aquino Cin |
| 27 | 316th | OF Austin Hays Bal |
| 28 | 333rd | 1B Evan White Sea |
| 29 | 340th | RP Will Smith Atl |