| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Ronald Acuna Jr. Atl |
| 2 | 23rd | 3B Rafael Devers Bos |
| 3 | 26th | SP Max Scherzer Was |
| 4 | 47th | SP Shane Bieber Cle |
| 5 | 50th | C J.T. Realmuto Phi |
| 6 | 71st | SP Pat Corbin Was |
| 7 | 74th | OF Jorge Soler KC |
| 8 | 95th | 1B Yulieski Gurriel Hou |
| 9 | 98th | OF Michael Conforto NYN |
| 10 | 119th | SS Corey Seager LAD |
| 11 | 122nd | SP Max Fried Atl |
| 12 | 143rd | SP Marcus Stroman NYN |
| 13 | 146th | 1B Trey Mancini Bal |
| 14 | 167th | SS Didi Gregorius Phi |
| 15 | 170th | OF Gregory Polanco Pit |
| 16 | 191st | RP Sean Doolittle Was |
| 17 | 194th | SP Lance McCullers Hou |
| 18 | 215th | SP Chris Archer Pit |
| 19 | 218th | 2B Robinson Cano NYN |
| 20 | 239th | SP Sandy Alcántra Mia |
| 21 | 242nd | OF Joc Pederson LAD |
| 22 | 263rd | OF Alex Verdugo Bos |
| 23 | 266th | 2B Starlin Castro Was |
| 24 | 287th | OF Wil Myers SD |
| 25 | 290th | RP Keone Kela Pit |
| 26 | 311th | SP Danny Duffy KC |
| 27 | 314th | 1B Albert Pujols LAA |
| 28 | 335th | SP Jonathan Gray Col |
| 29 | 338th | 3B Kyle Seager Sea |