| Round | Overall | Player |
|---|---|---|
| 1 | 12th | 3B Vladimir Guerrero Jr Tor |
| 2 | 13th | OF Yordan Alvarez Hou |
| 3 | 36th | SS Trea Turner Was |
| 4 | 37th | OF George Springer Hou |
| 5 | 60th | SP Justin Verlander Hou |
| 6 | 61st | 1B Max Muncy LAD |
| 7 | 84th | 2B Gavin Lux LAD |
| 8 | 85th | SP Frankie Montas Oak |
| 9 | 108th | OF David Dahl Tex |
| 10 | 109th | DH Nelson Cruz Min |
| 11 | 132nd | 1B Luke Voit NYA |
| 12 | 133rd | 2B Ryan McMahon Col |
| 13 | 156th | 3B Nick Solak Tex |
| 14 | 157th | SP Aaron Civale Cle |
| 15 | 180th | SP Spencer Howard Phi |
| 16 | 181st | OF Ian Happ ChN |
| 17 | 204th | SP Germán Márquez Col |
| 18 | 205th | OF Mark Canha Oak |
| 19 | 228th | SS Elvis Andrus Tex |
| 20 | 229th | OF Danny Santana Tex |
| 21 | 252nd | C Danny Jansen Tor |
| 22 | 253rd | SP J.A. Happ NYA |
| 23 | 276th | SS Luis Urias Mil |
| 24 | 277th | SP Joey Lucchesi SD |
| 25 | 300th | RP Hunter Harvey Bal |
| 26 | 301st | RP Ian Kennedy KC |
| 27 | 324th | SP Alex Wood LAD |
| 28 | 325th | RP Wade Davis Col |
| 29 | 348th | C Isiah Kiner-Falefa Tex |