| Round | Overall | Player |
|---|---|---|
| 1 | 6th | OF Juan Soto Was |
| 2 | 19th | 1B Matt Olson Oak |
| 3 | 30th | 3B Matt Chapman Oak |
| 4 | 43rd | SP Blake Snell SD |
| 5 | 54th | OF Giancarlo Stanton NYA |
| 6 | 67th | SP Tyler Glasnow TB |
| 7 | 78th | 2B D.J. LeMahieu NYA |
| 8 | 91st | 1B Carlos Santana KC |
| 9 | 102nd | C Mitch Garver Min |
| 10 | 115th | OF Lourdes Gurriel Tor |
| 11 | 126th | RP Brad Hand Cle |
| 12 | 139th | SS Jorge Polanco Min |
| 13 | 150th | OF Hunter Dozier KC |
| 14 | 163rd | SP Dakota Hudson StL |
| 15 | 174th | RP Hector Neris Phi |
| 16 | 187th | 3B Yandy Diaz TB |
| 17 | 198th | OF Nomar Mazara ChA |
| 18 | 211th | SP Michael Kopech ChA |
| 19 | 222nd | SS J.P. Crawford Sea |
| 20 | 235th | RP Hansel Robles Min |
| 21 | 246th | SP Yonny Chirinos TB |
| 22 | 259th | 2B Jonathan Schoop Det |
| 23 | 270th | SP Matt Shoemaker Tor |
| 24 | 283rd | SP Miles Mikolas StL |
| 25 | 294th | OF Randal Grichuk Tor |
| 26 | 307th | OF Joc Pederson LAD |
| 27 | 318th | C Yadier Molina StL |
| 28 | 331st | SP Dylan Cease ChA |
| 29 | 342nd | DH Shin-Soo Choo Tex |