| Round | Overall | Player |
|---|---|---|
| 1 | 4th | OF Christian Yelich Mil |
| 2 | 21st | SP Gerrit Cole NYA |
| 3 | 28th | 2B Jose Altuve Hou |
| 4 | 45th | 1B Anthony Rizzo ChN |
| 5 | 52nd | 1B Rhys Hoskins Phi |
| 6 | 69th | 3B Eugenio Suarez Cin |
| 7 | 76th | SP Mike Soroka Atl |
| 8 | 93rd | OF Starling Marte Ari |
| 9 | 100th | SS Marcus Semien Oak |
| 10 | 117th | RP Aroldis Chapman NYA |
| 11 | 124th | RP Kirby Yates SD |
| 12 | 141st | SP Eduardo Rodriguez Bos |
| 13 | 148th | OF Michael Brantley KC |
| 14 | 165th | 2B Brandon Lowe TB |
| 15 | 172nd | C Salvador Perez KC |
| 16 | 189th | 3B Giovanny Urshela NYA |
| 17 | 196th | SP Hyun-Jin Ryu Tor |
| 18 | 213th | RP Alex Colome ChA |
| 19 | 220th | SS Paul DeJong StL |
| 20 | 237th | C Christian Vazquez Bos |
| 21 | 244th | OF Kole Calhoun Ari |
| 22 | 261st | 1B Eric Hosmer SD |
| 23 | 268th | SP Zach Plesac Cle |
| 24 | 285th | SP Adrian Houser Mil |
| 25 | 292nd | SP Jon Lester ChN |
| 26 | 309th | SP Johnny Cueto SF |
| 27 | 316th | SP Wade Miley Cin |
| 28 | 333rd | DH Renato Núñez Bal |
| 29 | 340th | OF Jason Heyward ChN |