| Round | Overall | Player |
|---|---|---|
| 1 | 10th | 3B Nolan Arenado Col |
| 2 | 15th | 1B Freddie Freeman Atl |
| 3 | 34th | DH J.D. Martinez Bos |
| 4 | 39th | SP Jack Flaherty StL |
| 5 | 58th | OF Charlie Blackmon Col |
| 6 | 63rd | OF Luis Robert ChA |
| 7 | 82nd | SP Chris Paddack SD |
| 8 | 87th | SP Jesus Luzardo Oak |
| 9 | 106th | SS Adalberto Mondesí KC |
| 10 | 111th | OF Whit Merrifield KC |
| 11 | 130th | RP Kenley Jansen LAD |
| 12 | 135th | SP Dinelson Lamet SD |
| 13 | 154th | SP James Paxton NYA |
| 14 | 159th | SP Dylan Bundy LAA |
| 15 | 178th | RP Giovanny Gallegos StL |
| 16 | 183rd | OF Sam Hilliard Col |
| 17 | 202nd | 3B Miguel Andújar NYA |
| 18 | 207th | SS Didi Gregorius Phi |
| 19 | 226th | 2B Nico Hoerner ChN |
| 20 | 231st | OF Oscar Mercado Cle |
| 21 | 250th | 2B Robinson Cano NYN |
| 22 | 255th | C Omar Narváez Mil |
| 23 | 274th | SP Nate Pearson Tor |
| 24 | 279th | C Robinson Chirinos Tex |
| 25 | 298th | 1B Joey Votto Cin |
| 26 | 303rd | OF Mitch Haniger Sea |
| 27 | 322nd | 2B Mauricio Dubon SF |
| 28 | 327th | OF Yoshitomo Tsutsugo TB |
| 29 | 346th | SP Luis Severino NYA |