| Round | Overall | Player |
|---|---|---|
| 1 | 8th | SS Francisco Lindor Cle |
| 2 | 17th | 3B Jose Ramirez Cle |
| 3 | 32nd | OF Joey Gallo Tex |
| 4 | 41st | 1B Miguel Sano Min |
| 5 | 56th | OF Jorge Soler KC |
| 6 | 65th | DH Shohei Ohtani LAA |
| 7 | 80th | SS Wander Franco TB |
| 8 | 89th | SP Zach Wheeler Phi |
| 9 | 104th | SP MacKenzie Gore SD |
| 10 | 113th | C Yasmani Grandal ChA |
| 11 | 128th | RP Carlos Martinez StL |
| 12 | 137th | SP Corey Kluber Tex |
| 13 | 152nd | OF Dylan Carlson StL |
| 14 | 161st | SP Kenta Maeda Min |
| 15 | 176th | RP Nick Anderson TB |
| 16 | 185th | SP Mitch Keller Pit |
| 17 | 200th | SP Joe Musgrove Pit |
| 18 | 209th | 2B Tommy La Stella LAA |
| 19 | 224th | OF Avisail Garcia Mil |
| 20 | 233rd | RP Archie Bradley Ari |
| 21 | 248th | C Tom Murphy Sea |
| 22 | 257th | 2B Isan Diaz Mia |
| 23 | 272nd | SP Chris Archer Pit |
| 24 | 281st | OF Austin Hays Bal |
| 25 | 296th | 3B Kyle Seager Sea |
| 26 | 305th | 1B Mike Ford NYA |
| 27 | 320th | SS Niko Goodrum Det |
| 28 | 329th | OF Yasiel Puig Atl |
| 29 | 344th | SP Caleb Smith Mia |