| Round | Overall | Player |
|---|---|---|
| 1 | 1st | C Gary Sanchez NYA |
| 2 | 24th | SS Xander Bogaerts Bos |
| 3 | 25th | OF Charlie Blackmon Col |
| 4 | 48th | OF Giancarlo Stanton NYA |
| 5 | 49th | SP Tyler Glasnow TB |
| 6 | 72nd | SP Stephen Strasburg Was |
| 7 | 73rd | 1B Joshua Bell Was |
| 8 | 96th | C Yasmani Grandal ChA |
| 9 | 97th | 3B Jeff McNeil NYN |
| 10 | 120th | OF Nick Castellanos Cin |
| 11 | 121st | OF Willie Calhoun Tex |
| 12 | 144th | SP Sean Manaea Oak |
| 13 | 145th | OF Danny Santana Tex |
| 14 | 168th | SP Miles Mikolas StL |
| 15 | 169th | SP Joey Lucchesi SD |
| 16 | 192nd | 2B Jean Segura Phi |
| 17 | 193rd | SP Marco Gonzales Sea |
| 18 | 216th | SS Kevin Newman Pit |
| 19 | 217th | 1B Eric Hosmer SD |
| 20 | 240th | RP Will Smith Atl |
| 21 | 241st | 2B David Fletcher LAA |
| 22 | 264th | OF David Peralta Ari |
| 23 | 265th | SP Brad Keller KC |
| 24 | 288th | 3B Asdrubal Cabrera Was |
| 25 | 289th | OF Mike Yastrzemski SF |
| 26 | 312th | OF Wil Myers SD |
| 27 | 313th | C Austin Nola SD |
| 28 | 336th | SP Sandy Alcántra Mia |
| 29 | 337th | OF A.J. Pollock LAD |