| Round | Overall | Player |
|---|---|---|
| 1 | 4th | 3B Vladimir Guerrero Jr. Tor |
| 2 | 21st | OF Ronald Acuna Jr. Atl |
| 3 | 28th | OF Joey Gallo Tex |
| 4 | 45th | OF Bryce Harper Phi |
| 5 | 52nd | SP Luis Castillo Cin |
| 6 | 69th | SP Pat Corbin Was |
| 7 | 76th | OF Austin Meadows TB |
| 8 | 93rd | SP Trevor Bauer Cin |
| 9 | 100th | SP Hyun-Jin Ryu Tor |
| 10 | 117th | SP Julio Urías LAD |
| 11 | 124th | OF Franmil Reyes Cle |
| 12 | 141st | SP Sonny Gray Cin |
| 13 | 148th | SP Carlos Carrasco Cle |
| 14 | 165th | SP James Paxton NYA |
| 15 | 172nd | SP Jose Urquidy Hou |
| 16 | 189th | 3B Scott Kingery Phi |
| 17 | 196th | SS Dansby Swanson Atl |
| 18 | 213th | C Carson Kelly Ari |
| 19 | 220th | RP Brandon Workman Bos |
| 20 | 237th | RP Archie Bradley Ari |
| 21 | 244th | 1B Justin Smoak Ret |
| 22 | 261st | 2B Cesar Hernández Cle |
| 23 | 268th | RP Giovanny Gallegos StL |
| 24 | 285th | OF Brian Anderson Mia |
| 25 | 292nd | OF Yoshitomo Tsutsugo TB |
| 26 | 309th | 3B Ryan Mountcastle Bal |
| 27 | 316th | OF J.D. Davis NYN |
| 28 | 333rd | 1B Eric Thames Was |
| 29 | 340th | 2B Kolten Wong StL |