| Round | Overall | Player |
|---|---|---|
| 1 | 8th | 1B Peter Alonso NYN |
| 2 | 17th | SS Bo Bichette Tor |
| 3 | 32nd | 3B Manny Machado SD |
| 4 | 41st | OF Yordan Alvarez Hou |
| 5 | 56th | SP Chris Sale Bos |
| 6 | 65th | SP Justin Verlander Hou |
| 7 | 80th | 3B Josh Donaldson Min |
| 8 | 89th | OF Starling Marte Ari |
| 9 | 104th | OF Ramón Laureano Oak |
| 10 | 113th | SP Madison Bumgarner Ari |
| 11 | 128th | RP Craig Kimbrel ChN |
| 12 | 137th | 2B Brandon Lowe TB |
| 13 | 152nd | SP Marcus Stroman NYN |
| 14 | 161st | OF Gregory Polanco Pit |
| 15 | 176th | SP Dustin May LAD |
| 16 | 185th | SS Tim Anderson ChA |
| 17 | 200th | SP Aaron Civale Cle |
| 18 | 209th | C Francisco Mejia SD |
| 19 | 224th | SP Yonny Chirinos TB |
| 20 | 233rd | OF Domingo Santana Cle |
| 21 | 248th | 1B C.J. Cron Det |
| 22 | 257th | 2B Jonathan Schoop Det |
| 23 | 272nd | SP Zach Plesac Cle |
| 24 | 281st | 3B Carter Kieboom Was |
| 25 | 296th | C Roberto Perez Cle |
| 26 | 305th | SP John Means Bal |
| 27 | 320th | OF Avisail Garcia Mil |
| 28 | 329th | SP Martin Perez Bos |
| 29 | 344th | SP Cal Quantrill Cle |