| Round | Overall | Player |
|---|---|---|
| 1 | 1st | OF Mike Trout LAA |
| 2 | 24th | 3B Rafael Devers Bos |
| 3 | 25th | OF George Springer Hou |
| 4 | 48th | 2B Ketel Marte Ari |
| 5 | 49th | SS Marcus Semien Oak |
| 6 | 72nd | RP Kirby Yates SD |
| 7 | 73rd | SP Tyler Glasnow TB |
| 8 | 96th | SP Blake Snell SD |
| 9 | 97th | DH Nelson Cruz Min |
| 10 | 120th | 1B Yulieski Gurriel Hou |
| 11 | 121st | OF Hunter Dozier KC |
| 12 | 144th | SS Tim Anderson ChA |
| 13 | 145th | OF David Peralta Ari |
| 14 | 168th | C Tom Murphy Sea |
| 15 | 169th | SP Marcus Stroman NYN |
| 16 | 192nd | RP Will Smith Atl |
| 17 | 193rd | SP Michael Fiers Oak |
| 18 | 216th | SP Jeff Samardzija SF |
| 19 | 217th | 1B C.J. Cron Det |
| 20 | 240th | SP Garrett Richards SD |
| 21 | 241st | OF Kyle Lewis Sea |
| 22 | 264th | SP Forrest Whitley Hou |
| 23 | 265th | SP Anibal Sanchez Was |
| 24 | 288th | SP Caleb Smith Mia |
| 25 | 289th | 2B David Fletcher LAA |
| 26 | 312th | C James McCann ChA |
| 27 | 313th | 3B Asdrubal Cabrera Was |
| 28 | 336th | SP Rich Hill Min |
| 29 | 337th | OF Joc Pederson LAD |