| Round | Overall | Player |
|---|---|---|
| 1 | 7th | 1B Peter Alonso NYN |
| 2 | 18th | 3B Vladimir Guerrero Jr Tor |
| 3 | 31st | SS Bo Bichette Tor |
| 4 | 42nd | OF Willie Calhoun Tex |
| 5 | 55th | SP Stephen Strasburg Was |
| 6 | 66th | 2B Mike Moustakas Cin |
| 7 | 79th | SP Luis Castillo Cin |
| 8 | 90th | OF Jo Adell LAA |
| 9 | 103rd | OF Max Kepler Min |
| 10 | 114th | SP Brandon Woodruff Mil |
| 11 | 127th | SP Aaron Civale Cle |
| 12 | 138th | SP Trevor Bauer Cin |
| 13 | 151st | 2B Michael Chavis Bos |
| 14 | 162nd | 3B Nick Solak Tex |
| 15 | 175th | 1B Andrew Vaughn ChA |
| 16 | 186th | OF Gregory Polanco Pit |
| 17 | 199th | SP MacKenzie Gore SD |
| 18 | 210th | OF Avisail Garcia Mil |
| 19 | 223rd | SS J.P. Crawford Sea |
| 20 | 234th | SP Julio Teheran LAA |
| 21 | 247th | C Travis d'Arnaud Atl |
| 22 | 258th | C Adley Rutschman Bal |
| 23 | 271st | 2B Mauricio Dubon SF |
| 24 | 282nd | SP Adrian Houser Mil |
| 25 | 295th | SP Justus Sheffield Sea |
| 26 | 306th | SP Jordan Yamamoto Mia |
| 27 | 319th | SP Dylan Cease ChA |
| 28 | 330th | OF Cristian Pache Atl |
| 29 | 343rd | SP Brendan McKay TB |