| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | OF Ronald Acuna Jr. Atl |
| 2 | 22nd | SS Gleyber Torres NYA |
| 3 | 27th | 3B Yoan Moncada ChA |
| 4 | 46th | 1B Rhys Hoskins Phi |
| 5 | 51st | C Gary Sanchez NYA |
| 6 | 70th | 2B D.J. LeMahieu NYA |
| 7 | 75th | RP Aroldis Chapman NYA |
| 8 | 94th | SP Frankie Montas Oak |
| 9 | 99th | RP Roberto Osuna Hou |
| 10 | 118th | OF Lourdes Gurriel Tor |
| 11 | 123rd | SP Eduardo Rodriguez Bos |
| 12 | 142nd | RP Carlos Martinez StL |
| 13 | 147th | OF Justin Upton LAA |
| 14 | 166th | 3B Yandy Diaz TB |
| 15 | 171st | C Danny Jansen Tor |
| 16 | 190th | SP Dallas Keuchel ChA |
| 17 | 195th | SP Mike Foltynewicz Atl |
| 18 | 214th | SP Masahiro Tanaka NYA |
| 19 | 219th | SS Amed Rosario NYN |
| 20 | 238th | 1B Dan Vogelbach Sea |
| 21 | 243rd | SP Michael Kopech ChA |
| 22 | 262nd | SP Dylan Bundy LAA |
| 23 | 267th | OF Hunter Renfroe Bos |
| 24 | 286th | OF Shogo Akiyama Cin |
| 25 | 291st | 2B Brendan Rodgers Col |
| 26 | 310th | SP Reynaldo Lopez ChA |
| 27 | 315th | SP Alex Wood LAD |
| 28 | 334th | RP Jordan Hicks StL |
| 29 | 339th | 1B Dan Murphy Col |