| Round | Overall | Player |
|---|---|---|
| 1 | 9th | OF Mookie Betts LAD |
| 2 | 16th | OF Joey Gallo Tex |
| 3 | 33rd | 1B Matt Olson Oak |
| 4 | 40th | SS Javier Baez ChN |
| 5 | 57th | SP Justin Verlander Hou |
| 6 | 64th | 3B Eugenio Suarez Cin |
| 7 | 81st | SP Lucas Giolito ChA |
| 8 | 88th | 2B Ryan McMahon Col |
| 9 | 105th | OF Eddie Rosario Min |
| 10 | 112th | DH Khris Davis Oak |
| 11 | 129th | SP Sean Manaea Oak |
| 12 | 136th | C Sean Murphy Oak |
| 13 | 153rd | SP James Paxton NYA |
| 14 | 160th | SP Lance McCullers Hou |
| 15 | 177th | OF Mitch Haniger Sea |
| 16 | 184th | SS Paul DeJong StL |
| 17 | 201st | RP Mark Melancon Atl |
| 18 | 208th | 2B Starlin Castro Was |
| 19 | 225th | 3B Justin Turner LAD |
| 20 | 232nd | OF Yasiel Puig Atl |
| 21 | 249th | 1B Justin Smoak Ret |
| 22 | 256th | SP Steven Matz NYN |
| 23 | 273rd | C Roberto Perez Cle |
| 24 | 280th | 2B Garrett Hampson Col |
| 25 | 297th | OF Mark Canha Oak |
| 26 | 304th | SP Miles Mikolas StL |
| 27 | 321st | SP Matt Shoemaker Tor |
| 28 | 328th | SP Domingo German NYA |
| 29 | 345th | SP Nathan Eovaldi Bos |