| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | OF Ronald Acuna Jr. Atl |
| 2 | 23rd | 2B Ozzie Albies Atl |
| 3 | 26th | SP Jack Flaherty StL |
| 4 | 47th | OF Giancarlo Stanton NYA |
| 5 | 50th | 3B Vladimir Guerrero Jr. Tor |
| 6 | 71st | 1B Rhys Hoskins Phi |
| 7 | 74th | SP Jose Berrios Min |
| 8 | 95th | C J.T. Realmuto Phi |
| 9 | 98th | 3B Yoan Moncada ChA |
| 10 | 119th | OF Franmil Reyes Cle |
| 11 | 122nd | 2B Gavin Lux LAD |
| 12 | 143rd | SS Adalberto Mondesí KC |
| 13 | 146th | SP Julio Urías LAD |
| 14 | 167th | SP Dylan Bundy LAA |
| 15 | 170th | OF Jo Adell LAA |
| 16 | 191st | 2B Michael Chavis Bos |
| 17 | 194th | SP Joey Lucchesi SD |
| 18 | 215th | 3B Miguel Andújar NYA |
| 19 | 218th | OF Oscar Mercado Cle |
| 20 | 239th | 1B Evan White Sea |
| 21 | 242nd | C Carson Kelly Ari |
| 22 | 263rd | RP Archie Bradley Ari |
| 23 | 266th | RP Ian Kennedy KC |
| 24 | 287th | OF Mitch Haniger Sea |
| 25 | 290th | SP J.A. Happ NYA |
| 26 | 311th | OF Dylan Carlson StL |
| 27 | 314th | RP Keone Kela Pit |
| 28 | 335th | SS Andrelton Simmons LAA |
| 29 | 338th | SP Adam Wainwright StL |