| Round | Overall | Player |
|---|---|---|
| 1 | 12th | 3B Vladimir Guerrero Jr Tor |
| 2 | 13th | OF Bryce Harper Phi |
| 3 | 36th | 1B Matt Olson Oak |
| 4 | 37th | SS Xander Bogaerts Bos |
| 5 | 60th | 2B Gavin Lux LAD |
| 6 | 61st | OF Giancarlo Stanton NYA |
| 7 | 84th | OF Joey Gallo NYA |
| 8 | 85th | DH Shohei Ohtani LAA |
| 9 | 108th | SP Mike Soroka Atl |
| 10 | 109th | 1B Miguel Sano Min |
| 11 | 132nd | OF Nick Castellanos Cin |
| 12 | 133rd | DH Nelson Cruz Min |
| 13 | 156th | 3B Austin Riley Atl |
| 14 | 157th | SS Bobby Witt Jr. KC |
| 15 | 180th | 3B Giovanny Urshela NYA |
| 16 | 181st | OF Mitch Haniger Sea |
| 17 | 204th | RP Amir Garrett Cin |
| 18 | 205th | RP Jordan Romano Tor |
| 19 | 228th | 2B Ryan McMahon Col |
| 20 | 229th | RP Daniel Bard Col |
| 21 | 252nd | C Adley Rutschman Bal |
| 22 | 253rd | SS Paul DeJong StL |
| 23 | 276th | 3B Nick Solak Tex |
| 24 | 277th | SP David Price LAD |
| 25 | 300th | SP Taijuan Walker NYN |
| 26 | 301st | OF Jesse Winker Cin |
| 27 | 324th | SP Carlos Rodon ChA |
| 28 | 325th | SP Kwang-Hyun Kim StL |
| 29 | 348th | C Jorge Alfaro Mia |