| Round | Overall | Player |
|---|---|---|
| 1 | 1st | SS Fernando Tatis Jr. SD |
| 2 | 24th | 2B Jose Altuve Hou |
| 3 | 25th | OF Aaron Judge NYA |
| 4 | 48th | SP Max Scherzer NYN |
| 5 | 49th | OF Cody Bellinger ChN |
| 6 | 72nd | 1B Jared Walsh LAA |
| 7 | 73rd | 3B Kris Bryant Col |
| 8 | 96th | SP Chris Sale Bos |
| 9 | 97th | OF Austin Meadows Det |
| 10 | 120th | SP Framber Valdez Hou |
| 11 | 121st | 3B Ryan Mountcastle Bal |
| 12 | 144th | RP Aroldis Chapman NYA |
| 13 | 145th | RP Jordan Romano Tor |
| 14 | 168th | SS Dansby Swanson Atl |
| 15 | 169th | RP Kenley Jansen Bos |
| 16 | 192nd | SP Yu Darvish SD |
| 17 | 193rd | SP Blake Snell SD |
| 18 | 216th | 1B Nathaniel Lowe Tex |
| 19 | 217th | OF Adam Duvall Atl |
| 20 | 240th | SP Gabriel Ynoa Bal |
| 21 | 241st | 1B Joey Votto Cin |
| 22 | 264th | 2B Kolten Wong Mil |
| 23 | 265th | SP Patrick Sandoval LAA |
| 24 | 288th | SP Yusei Kikuchi Tor |
| 25 | 289th | OF Kyle Lewis Sea |
| 26 | 312th | SP Josiah Gray Was |
| 27 | 313th | C Travis d'Arnaud Atl |
| 28 | 336th | OF A.J. Pollock ChA |
| 29 | 337th | SS Didi Gregorius Phi |