| Round | Overall | Player |
|---|---|---|
| 1 | 11th | OF Mike Trout LAA |
| 2 | 14th | SS Bo Bichette Tor |
| 3 | 35th | 3B Nolan Arenado StL |
| 4 | 38th | SP Julio Urías LAD |
| 5 | 59th | SP Max Fried Atl |
| 6 | 62nd | OF Joey Gallo LAD |
| 7 | 83rd | 2B Jazz Chisholm Jr. Mia |
| 8 | 86th | RP Raisel Iglesias Atl |
| 9 | 107th | RP Liam Hendriks ChA |
| 10 | 110th | SP Jose Berrios Tor |
| 11 | 131st | OF Dylan Carlson StL |
| 12 | 134th | 1B C.J. Cron Col |
| 13 | 155th | SP Sean Manaea SD |
| 14 | 158th | SP Germán Márquez Col |
| 15 | 179th | 2B Cavan Biggio Tor |
| 16 | 182nd | SS Jeremy Pena Hou |
| 17 | 203rd | OF Ramón Laureano Oak |
| 18 | 206th | SS Noelvi Marte Cin |
| 19 | 227th | OF Avisail Garcia Mia |
| 20 | 230th | OF Jasson Dominguez NYA |
| 21 | 251st | SP Nathan Eovaldi Bos |
| 22 | 254th | SS Marcelo Mayer Bos |
| 23 | 275th | 1B Jesus Aguilar Mia |
| 24 | 278th | OF Zac Veen Col |
| 25 | 299th | C Sean Murphy Atl |
| 26 | 302nd | 1B Bobby Bradley Cle |
| 27 | 323rd | 3B Yandy Diaz TB |
| 28 | 326th | OF Harrison Bader StL |
| 29 | 347th | OF Gavin Sheets ChA |