| Round | Overall | Player |
|---|---|---|
| 1 | 3rd | OF Juan Soto SD |
| 2 | 22nd | SS Xander Bogaerts SD |
| 3 | 27th | 1B Peter Alonso NYN |
| 4 | 46th | OF Giancarlo Stanton NYA |
| 5 | 51st | SP Sandy Alcántra Mia |
| 6 | 70th | 2B Jonathan India Cin |
| 7 | 75th | SS Trevor Story Bos |
| 8 | 94th | OF Riley Greene Det |
| 9 | 99th | SP Frankie Montas NYA |
| 10 | 118th | DH J.D. Martinez Bos |
| 11 | 123rd | RP Emmanuel Clase Cle |
| 12 | 142nd | 3B Justin Turner LAD |
| 13 | 147th | SP Aaron Civale Cle |
| 14 | 166th | C Willson Contreras StL |
| 15 | 171st | SP Adam Wainwright StL |
| 16 | 190th | SP Charlie Morton Atl |
| 17 | 195th | SP Eduardo Rodriguez Det |
| 18 | 214th | SP Jack Leiter Tex |
| 19 | 219th | SP Jose Urquidy Hou |
| 20 | 238th | OF Andrew McCutchen Mil |
| 21 | 243rd | C Gary Sanchez Min |
| 22 | 262nd | 1B Jonathan Schoop Det |
| 23 | 267th | OF Taylor Trammell Sea |
| 24 | 286th | SS J.P. Crawford Sea |
| 25 | 291st | SP Taijuan Walker Phi |
| 26 | 310th | RP Gregory Soto Det |
| 27 | 315th | RP Matt Barnes Bos |
| 28 | 334th | OF Justin Upton LAA |
| 29 | 339th | OF Max Kepler Min |