| Round | Overall | Player |
|---|---|---|
| 1 | 12th | OF Bryce Harper Phi |
| 2 | 13th | 1B Freddie Freeman LAD |
| 3 | 36th | SS Bobby Witt Jr. KC |
| 4 | 37th | SP Corbin Burnes Mil |
| 5 | 60th | 3B Matt Chapman Tor |
| 6 | 61st | OF Franmil Reyes Cle |
| 7 | 84th | SP Alek Manoah Tor |
| 8 | 85th | SS Tim Anderson ChA |
| 9 | 108th | SS Jorge Polanco Min |
| 10 | 109th | SP Shane Baz TB |
| 11 | 132nd | 2B Gavin Lux LAD |
| 12 | 133rd | OF Brennen Davis ChN |
| 12 | 133rd | 3B Brennen Davis Det |
| 13 | 156th | OF Josh Lowe TB |
| 14 | 157th | SP Luis Severino NYA |
| 15 | 180th | SS Anthony Volpe NYA |
| 16 | 181st | 2B Ryan McMahon Col |
| 17 | 204th | 1B Luke Voit SD |
| 18 | 205th | SP Dakota Hudson StL |
| 19 | 228th | DH Nelson Cruz Was |
| 20 | 229th | SP Reid Detmers LAA |
| 21 | 252nd | 3B Miguel Vargas LAD |
| 22 | 253rd | C Gabriel Moreno Tor |
| 23 | 276th | 3B Jose Miranda Min |
| 24 | 277th | SP Jesus Luzardo Mia |
| 25 | 300th | RP Jacob McGee SF |
| 26 | 301st | RP Scott Barlow KC |
| 27 | 324th | OF Robbie Grossman Det |
| 28 | 325th | SP Miles Mikolas StL |
| 29 | 348th | SP Nick Lodolo Cin |