| Round | Overall | Player |
|---|---|---|
| 1 | 4th | OF Juan Soto SD |
| 2 | 21st | 2B Jose Altuve Hou |
| 3 | 28th | SP Julio Urías LAD |
| 4 | 45th | 1B Paul Goldschmidt StL |
| 5 | 52nd | 3B Nolan Arenado StL |
| 6 | 69th | OF Giancarlo Stanton NYA |
| 7 | 76th | SP Jose Berrios Tor |
| 8 | 93rd | SS Javier Baez Det |
| 9 | 100th | OF Christian Yelich Mil |
| 10 | 117th | SP Carlos Rodon SF |
| 11 | 124th | OF Jesse Winker Mil |
| 12 | 141st | RP Corey Knebel LAD |
| 13 | 148th | 2B D.J. LeMahieu NYA |
| 14 | 165th | SP Ranger Suarez Phi |
| 15 | 172nd | RP Matt Barnes Bos |
| 16 | 189th | 1B Anthony Rizzo NYA |
| 17 | 196th | C Willson Contreras StL |
| 18 | 213th | OF Kike Hernandez Bos |
| 19 | 220th | SP Germán Márquez Col |
| 20 | 237th | 3B Jeimer Candelario Det |
| 21 | 244th | RP Joe Barlow Tex |
| 22 | 261st | SP Drew Rasmussen TB |
| 23 | 268th | SS J.P. Crawford Sea |
| 24 | 285th | SP Chris Sale Bos |
| 25 | 292nd | OF Andrew McCutchen Mil |
| 26 | 309th | SP Nestor Cortes Jr. NYA |
| 27 | 316th | C Connor Joe Col |
| 28 | 333rd | SP Miles Mikolas StL |
| 29 | 340th | OF Tommy Pham Cin |