| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | 1B Vladimir Guerrero Jr. Tor |
| 2 | 23rd | SP Gerrit Cole NYA |
| 3 | 26th | 2B Marcus Semien Tex |
| 4 | 47th | SP Max Fried Atl |
| 5 | 50th | SP Freddy Peralta Mil |
| 6 | 71st | SP Logan Webb SF |
| 7 | 74th | 3B Matt Chapman Tor |
| 8 | 95th | OF Austin Meadows Det |
| 9 | 98th | SS Jorge Polanco Min |
| 10 | 119th | 1B Joey Votto Cin |
| 11 | 122nd | OF Starling Marte NYN |
| 12 | 143rd | RP Corey Knebel LAD |
| 13 | 146th | SP Casey Mize Det |
| 14 | 167th | OF Seiya Suzuki ChN |
| 15 | 170th | SP Luis Castillo Cin |
| 16 | 191st | SS Adalberto Mondesà KC |
| 17 | 194th | C Willson Contreras StL |
| 18 | 215th | OF Andrew Vaughn ChA |
| 19 | 218th | RP Gregory Soto Det |
| 20 | 239th | SP Shane Baz TB |
| 21 | 242nd | OF Trent Grisham SD |
| 22 | 263rd | C Keibert Ruiz Was |
| 23 | 266th | 1B Ty France Sea |
| 24 | 287th | RP Camilo Doval SF |
| 25 | 290th | RP Tanner Rainey Was |
| 26 | 311th | SP Luis Patino TB |
| 27 | 314th | SP Matt Manning Det |
| 28 | 335th | SP Trevor Bauer LAD |
| 29 | 338th | SS Diego Castillo Pit |