| Round | Overall | Player |
|---|---|---|
| 1 | 6th | DH Shohei Ohtani LAA |
| 2 | 19th | 3B Manny Machado SD |
| 3 | 30th | OF Kyle Schwarber Phi |
| 4 | 43rd | SP Shane Bieber Cle |
| 5 | 54th | SS Xander Bogaerts SD |
| 6 | 67th | SP Dylan Cease ChA |
| 7 | 78th | OF Cedric Mullins Bal |
| 8 | 91st | C Salvador Perez KC |
| 9 | 102nd | SP Robbie Ray Sea |
| 10 | 115th | 1B Christian Walker Ari |
| 11 | 126th | 2B Andrés Gimenez Cle |
| 12 | 139th | OF Anthony Santander Bal |
| 13 | 150th | SP Jesus Luzardo Mia |
| 14 | 163rd | SP Reid Detmers LAA |
| 15 | 174th | OF Seiya Suzuki ChN |
| 16 | 187th | SS Tim Anderson ChA |
| 17 | 198th | 2B Miguel Vargas LAD |
| 18 | 211th | SP Taijuan Walker Phi |
| 19 | 222nd | 1B Trey Mancini ChN |
| 20 | 235th | OF Oscar Gonzalez Cle |
| 21 | 246th | SP Hunter Brown Hou |
| 22 | 259th | 3B Yandy Diaz TB |
| 23 | 270th | SP Trevor Rogers Mia |
| 24 | 283rd | SS Oswaldo Cabrera NYA |
| 25 | 294th | SP Ryan Pepiot LAD |
| 26 | 307th | SP Eric Lauer Mil |
| 27 | 318th | SP Germán Márquez Col |
| 28 | 331st | OF Jasson Dominguez NYA |
| 29 | 342nd | 1B Dan Vogelbach NYN |