| Round | Overall | Player |
|---|---|---|
| 1 | 9th | SS Trea Turner Phi |
| 2 | 16th | 3B Rafael Devers Bos |
| 3 | 33rd | C Adley Rutschman Bal |
| 4 | 40th | SP Alek Manoah Tor |
| 5 | 57th | RP Devin Williams Mil |
| 6 | 64th | OF Corbin Carroll Ari |
| 7 | 81st | SP Zac Gallen Ari |
| 8 | 88th | 1B Vinnie Pasquantino KC |
| 9 | 105th | SP Luis Garcia Hou |
| 10 | 112th | OF Masataka Yoshida Bos |
| 11 | 129th | 2B Brandon Lowe TB |
| 12 | 136th | RP Kenley Jansen Bos |
| 13 | 153rd | 1B C.J. Cron LAA |
| 14 | 160th | OF Jarred Kelenic Sea |
| 15 | 177th | C Tyler Stephenson Cin |
| 16 | 184th | 3B Jose Miranda Min |
| 17 | 201st | OF Joey Gallo Min |
| 18 | 208th | RP Raisel Iglesias Atl |
| 19 | 225th | OF Oscar Colas ChA |
| 20 | 232nd | SP Brady Singer KC |
| 21 | 249th | SP Graham Ashcraft Cin |
| 22 | 256th | 2B Jorge Polanco Min |
| 23 | 273rd | SP MacKenzie Gore Was |
| 24 | 280th | SS Isaac Paredes TB |
| 25 | 297th | RP A.J. Minter Atl |
| 26 | 304th | 2B David Villar SF |
| 27 | 321st | SP Zach Eflin TB |
| 28 | 328th | RP Pete Fairbanks TB |
| 29 | 345th | SP Ryne Nelson Ari |