| Round | Overall | Player |
|---|---|---|
| 1 | 10th | OF Aaron Judge NYA |
| 2 | 15th | OF Kyle Tucker Hou |
| 3 | 34th | SP Zach Wheeler Phi |
| 4 | 39th | SP Gerrit Cole NYA |
| 5 | 58th | SP Kevin Gausman Tor |
| 6 | 63rd | SP Zac Gallen Ari |
| 7 | 82nd | SP Kodai Senga NYN |
| 8 | 87th | SP Logan Gilbert Sea |
| 9 | 106th | OF Bryan Reynolds Pit |
| 10 | 111th | SP Jose Berrios Tor |
| 11 | 130th | RP Devin Williams Mil |
| 12 | 135th | SP Joe Musgrove SD |
| 13 | 154th | 2B Luis Arraez SD |
| 14 | 159th | SP Sonny Gray StL |
| 15 | 178th | OF Masataka Yoshida Bos |
| 16 | 183rd | SP Eury Perez Mia |
| 17 | 202nd | SS Ha-seong Kim SD |
| 18 | 207th | 1B Andrew Vaughn ChA |
| 19 | 226th | 3B Noelvi Marte Cin |
| 20 | 231st | C Willson Contreras StL |
| 21 | 250th | OF Jung Hoo Lee SF |
| 22 | 255th | SP Michael King SD |
| 23 | 274th | OF TJ Friedl Cin |
| 24 | 279th | RP Kyle Finnegan Was |
| 25 | 298th | 1B Ty France Sea |
| 26 | 303rd | SS Zach Neto LAA |
| 27 | 322nd | 2B Vaughn Grissom Bos |
| 28 | 327th | C Luis Campusano SD |
| 29 | 346th | 3B Ezequiel Duran Tex |