| Round | Overall | Player |
|---|---|---|
| 1 | 1st | OF Ronald Acuna Jr. Atl |
| 2 | 24th | 1B Vladimir Guerrero Jr Tor |
| 3 | 25th | 3B Gunnar Henderson Bal |
| 4 | 48th | C Adley Rutschman Bal |
| 5 | 49th | OF Kyle Schwarber Phi |
| 6 | 72nd | RP Raisel Iglesias Atl |
| 7 | 73rd | 2B Ketel Marte Ari |
| 8 | 96th | RP David Bednar Pit |
| 9 | 97th | SP Shane Bieber Cle |
| 10 | 120th | 1B Yandy Diaz TB |
| 11 | 121st | 3B Ke'Bryan Hayes Pit |
| 12 | 144th | OF Riley Greene Det |
| 13 | 145th | 2B Nolan Gorman StL |
| 14 | 168th | RP Adbert Alzolay ChN |
| 15 | 169th | SS Carlos Correa Min |
| 16 | 192nd | OF Jackson Chourio Mil |
| 17 | 193rd | C Sean Murphy Atl |
| 18 | 216th | SP Luis Severino NYN |
| 19 | 217th | SS Junior Caminero TB |
| 20 | 240th | OF MJ Melendez KC |
| 21 | 241st | SP Jonathan Gray Tex |
| 22 | 264th | SS Gavin Lux LAD |
| 23 | 265th | SP Reid Detmers LAA |
| 24 | 288th | 3B Brett Baty NYN |
| 25 | 289th | SP Mike Soroka ChA |
| 26 | 312th | SP Garrett Crochet ChA |
| 27 | 313th | 1B Ryan Noda Oak |
| 28 | 336th | SP Jordan Hicks SF |
| 29 | 337th | OF James Wood Was |