| Round | Overall | Player |
|---|---|---|
| 1 | 11th | 1B Pete Alonso NYN |
| 2 | 14th | 3B Austin Riley Atl |
| 3 | 35th | SS Bo Bichette Tor |
| 4 | 38th | 1B Triston Casas Bos |
| 5 | 59th | C Will Smith LAD |
| 6 | 62nd | OF Byron Buxton Min |
| 7 | 83rd | OF Eloy Jimenez Bal |
| 8 | 86th | OF Jazz Chisholm Jr. NYA |
| 9 | 107th | RP Evan Phillips LAD |
| 10 | 110th | RP Andres Munoz Sea |
| 11 | 131st | RP Ryan Helsley StL |
| 12 | 134th | 2B Zack Gelof Oak |
| 13 | 155th | SP Yu Darvish SD |
| 14 | 158th | SP Carlos Rodon NYA |
| 15 | 179th | OF Tyler O'Neill Bos |
| 16 | 182nd | 2B Jonathan India Cin |
| 17 | 203rd | OF Chas McCormick Hou |
| 18 | 206th | 3B Ryan McMahon Col |
| 19 | 227th | 1B Ryan Mountcastle Bal |
| 20 | 230th | SS Ezequiel Tovar Col |
| 21 | 251st | 2B Edouard Julien Min |
| 22 | 254th | OF Parker Meadows Det |
| 23 | 275th | SP Miles Mikolas StL |
| 24 | 278th | SP J.P. France Hou |
| 25 | 299th | SP Reese Olson Det |
| 26 | 302nd | SP Ryne Nelson Ari |
| 27 | 323rd | OF Colton Cowser Bal |
| 28 | 326th | C Alejandro Kirk Tor |
| 29 | 347th | SP Clarke Schmidt NYA |