| Round | Overall | Player |
|---|---|---|
| 1 | 7th | 1B Vladimir Guerrero Jr. Tor |
| 2 | 18th | OF Julio Rodriguez Sea |
| 3 | 31st | SS Corey Seager Tex |
| 4 | 42nd | OF Oneil Cruz Pit |
| 5 | 55th | 2B Jose Altuve Hou |
| 6 | 66th | SP Michael King SD |
| 7 | 79th | OF Adolis Garcia Tex |
| 8 | 90th | SP Pablo Lopez Min |
| 9 | 103rd | SP Tanner Bibee Cle |
| 10 | 114th | SP Zac Gallen Ari |
| 11 | 127th | C Yainer Diaz Hou |
| 12 | 138th | 3B Max Muncy LAD |
| 13 | 151st | RP Tanner Scott LAD |
| 14 | 162nd | RP David Bednar Pit |
| 15 | 175th | OF Heliot Ramos SF |
| 16 | 186th | SP Mitch Keller Pit |
| 17 | 199th | 2B Kristian Campbell Bos |
| 18 | 210th | RP Carlos Estevez KC |
| 19 | 223rd | 3B Cam Smith Hou |
| 20 | 234th | SP Yusei Kikuchi LAA |
| 21 | 247th | SP Jesus Luzardo Phi |
| 22 | 258th | SP Reese Olson Det |
| 23 | 271st | OF Garrett Mitchell Mil |
| 24 | 282nd | 1B Tyler Soderstrom Oak |
| 25 | 295th | OF Daulton Varsho Tor |
| 26 | 306th | SS Oswaldo Cabrera NYA |
| 27 | 319th | 3B Zach Dezenzo Hou |
| 28 | 330th | SP Jack Leiter Tex |
| 29 | 343rd | C Kyle Higashioka Tex |