| Round | Overall | Player |
|---|---|---|
| 1 | 10th | SS Francisco Lindor NYN |
| 2 | 15th | 1B Matt Olson Atl |
| 3 | 34th | SP Framber Valdez Hou |
| 4 | 39th | RP Josh Hader Hou |
| 5 | 58th | SP Logan Webb SF |
| 6 | 63rd | SP Dylan Cease SD |
| 7 | 82nd | OF Ian Happ ChN |
| 8 | 87th | OF Bryan Reynolds Pit |
| 9 | 106th | 3B Eugenio Suarez Ari |
| 10 | 111th | SS Dansby Swanson ChN |
| 11 | 130th | RP Jeff Hoffman Tor |
| 12 | 135th | OF Brandon Nimmo NYN |
| 13 | 154th | 2B Gleyber Torres Det |
| 14 | 159th | SP Jose Berrios Tor |
| 15 | 178th | C Logan O'Hoppe LAA |
| 16 | 183rd | OF Nick Castellanos Phi |
| 17 | 202nd | RP Kenley Jansen LAA |
| 18 | 207th | SP Chris Bassitt Tor |
| 19 | 226th | OF George Springer Tor |
| 20 | 231st | SP Jameson Taillon ChN |
| 21 | 250th | SP Erick Fedde StL |
| 22 | 255th | SP Nick Pivetta SD |
| 23 | 274th | C Joey Bart Pit |
| 24 | 279th | 1B Joshua Bell Was |
| 25 | 298th | OF Andrew McCutchen Pit |
| 26 | 303rd | 2B Willi Castro Min |
| 27 | 322nd | RP Chris Martin Tex |
| 28 | 327th | SP Aaron Civale Mil |
| 29 | 346th | SP Andrew Heaney Pit |