| Round | Overall | Player |
|---|---|---|
| 1 | 10th | SS Gunnar Henderson Bal |
| 2 | 15th | SP Paul Skenes Pit |
| 3 | 34th | 3B Manny Machado SD |
| 4 | 39th | OF Oneil Cruz Pit |
| 5 | 58th | SP Yoshinobu Yamamoto LAD |
| 6 | 63rd | RP Edwin Diaz NYN |
| 7 | 82nd | C Salvador Perez KC |
| 8 | 87th | OF Riley Greene Det |
| 9 | 106th | SP Zac Gallen Ari |
| 10 | 111th | 3B Junior Caminero TB |
| 11 | 130th | OF Steven Kwan Cle |
| 12 | 135th | 3B Alec Bohm Phi |
| 13 | 154th | 2B Brice Turang Mil |
| 14 | 159th | SP Seth Lugo KC |
| 15 | 178th | OF Josh Lowe TB |
| 16 | 183rd | RP Kenley Jansen LAA |
| 17 | 202nd | SP Drew Rasmussen TB |
| 18 | 207th | 1B Nathaniel Lowe Was |
| 19 | 226th | SP Yu Darvish SD |
| 20 | 231st | 2B Brandon Lowe TB |
| 21 | 250th | SP Jeffrey Springs Oak |
| 22 | 255th | 2B Willi Castro Min |
| 23 | 274th | RP Jason Adam SD |
| 24 | 279th | SP Nestor Cortes Jr. Mil |
| 25 | 298th | OF Luke Raley Sea |
| 26 | 303rd | SP Grant Holmes Atl |
| 27 | 322nd | RP Griffin Jax Min |
| 28 | 327th | C Alejandro Kirk Tor |
| 29 | 346th | OF Heston Kjerstad Bal |