| Round | Overall | Player |
|---|---|---|
| 1 | 2nd | DH Shohei Ohtani LAD |
| 2 | 23rd | SS Trea Turner Phi |
| 3 | 26th | OF Jarren Duran Bos |
| 4 | 47th | SP Garrett Crochet Bos |
| 5 | 50th | 2B Ozzie Albies Atl |
| 6 | 71st | RP Ryan Helsley StL |
| 7 | 74th | SP Tyler Glasnow LAD |
| 8 | 95th | 1B Christian Walker Hou |
| 9 | 98th | SP Spencer Schwellenbach Atl |
| 10 | 119th | SS Bo Bichette Tor |
| 11 | 122nd | SP Shane McClanahan TB |
| 12 | 143rd | OF Christian Yelich Mil |
| 13 | 146th | OF Mike Trout LAA |
| 14 | 167th | C J.T. Realmuto Phi |
| 15 | 170th | SP Robbie Ray SF |
| 16 | 191st | RP Pete Fairbanks TB |
| 17 | 194th | 3B Nolan Arenado StL |
| 18 | 215th | SP Taj Bradley TB |
| 19 | 218th | SP Spencer Arrighetti Hou |
| 20 | 239th | 1B Ryan Mountcastle Bal |
| 21 | 242nd | OF TJ Friedl Cin |
| 22 | 263rd | OF Nolan Jones Cle |
| 23 | 266th | SS Trevor Story Bos |
| 24 | 287th | C Connor Wong Bos |
| 25 | 290th | 1B Colt Keith Det |
| 26 | 311th | SP Will Warren NYA |
| 27 | 314th | SP Matt Boyd ChN |
| 28 | 335th | SP Cody Bradford Tex |
| 29 | 338th | RP Edwin Uceta TB |