| Round | Overall | Player |
|---|---|---|
| 1 | 8th | RP Emmanuel Clase Cle |
| 2 | 17th | SP Tarik Skubal Det |
| 3 | 32nd | C William Contreras Mil |
| 4 | 41st | OF Kyle Schwarber Phi |
| 5 | 56th | 3B Matt Chapman SF |
| 6 | 65th | RP Raisel Iglesias Atl |
| 7 | 80th | OF Anthony Santander Tor |
| 8 | 89th | OF Taylor Ward LAA |
| 9 | 104th | SP Justin Steele ChN |
| 10 | 113th | OF Randy Arozarena Sea |
| 11 | 128th | SS Dansby Swanson ChN |
| 12 | 137th | 1B Yandy Diaz TB |
| 13 | 152nd | 2B Jonathan India KC |
| 14 | 161st | SP Cristopher Sanchez Phi |
| 15 | 176th | 1B Andrew Vaughn ChA |
| 16 | 185th | SP Tanner Houck Bos |
| 17 | 200th | 3B Ryan McMahon Col |
| 18 | 209th | SP Chris Bassitt Tor |
| 19 | 224th | RP Jason Foley Det |
| 20 | 233rd | 2B Jake Cronenworth SD |
| 21 | 248th | SP Michael Wacha KC |
| 22 | 257th | 1B Michael Busch ChN |
| 23 | 272nd | OF Christopher Morel TB |
| 24 | 281st | SP Mitch Keller Pit |
| 25 | 296th | SP Jameson Taillon ChN |
| 26 | 305th | SP Brady Singer Cin |
| 27 | 320th | OF Jo Adell LAA |
| 28 | 329th | SS J.P. Crawford Sea |
| 29 | 344th | 3B Matt Vierling Det |