| Round | Overall | Player |
|---|---|---|
| 1 | 6th | SS Mookie Betts LAD |
| 2 | 19th | 1B Bryce Harper Phi |
| 3 | 30th | 2B Jazz Chisholm Jr. NYA |
| 4 | 43rd | SP Cole Ragans KC |
| 5 | 54th | SS CJ Abrams Was |
| 6 | 67th | RP Mason Miller Oak |
| 7 | 78th | SP Bailey Ober Min |
| 8 | 91st | RP Andres Munoz Sea |
| 9 | 102nd | SP Joe Ryan Min |
| 10 | 115th | RP Jhoan Duran Min |
| 11 | 126th | SP Spencer Strider Atl |
| 12 | 139th | OF Brandon Nimmo NYN |
| 13 | 150th | SS Xander Bogaerts SD |
| 14 | 163rd | SS Masyn Winn StL |
| 15 | 174th | OF Pete Crow-Armstrong ChN |
| 16 | 187th | OF Tyler O'Neill Bal |
| 17 | 198th | C Austin Wells NYA |
| 18 | 211th | SS Zach Neto LAA |
| 19 | 222nd | SP Sean Manaea NYN |
| 20 | 235th | SP Kumar Rocker Tex |
| 21 | 246th | OF Jake McCarthy Ari |
| 22 | 259th | OF Parker Meadows Det |
| 23 | 270th | 1B Christian Encarnacion-Strand Cin |
| 24 | 283rd | C Ivan Herrera StL |
| 25 | 294th | SP Jackson Jobe Det |
| 26 | 307th | RP Ben Joyce LAA |
| 27 | 318th | SP Hayden Birdsong SF |
| 28 | 331st | 2B Otto Lopez Mia |
| 29 | 342nd | SP Tobias Myers Mil |