| Week | Add | Drop |
| Week 5 |
Round 1: 1B Chad Tracy - Ari |
Round 1: SP Tomo Ohka - Mon |
| Week 6 |
Round 1: SS Juan Uribe - ChA Round 2: SP Zack Greinke - KC |
Round 1: RP Damaso Marte - ChA Round 2: OF Raul Mondesi - Ana |
| Week 7 |
Round 1: SP Chris Carpenter - StL |
Round 1: SP Gil Meche - Sea |
| Week 9 |
Round 1: SP Jose Acevedo - Cin |
Round 1: SP John Lackey - Ana |
| Week 10 |
Round 1: 2B Chone Figgins - Ana | |
| Week 12 |
Round 1: SS Nomar Garciaparra - ChN |
Round 1: 1B Josh Phelps - Cle |
| Week 16 |
Round 1: SP Brandon Claussen - Cin |
Round 1: SP Jose Acevedo - Cin Round 2: 1B Chad Tracy - Ari |
| Week 17 |
Round 1: OF Delmon Young - TB | |
| Week 18 |
Round 1: OF Jayson Werth - LA Round 2: 2B Roberto Alomar - ChA |
Round 2: SS Alex Cintron - Ari |
| Week 19 |
Round 1: 1B Ben Broussard - Cle |
Round 1: OF Raul Ibanez - Sea |
| Week 20 |
Round 2: SP Brandon Claussen - Cin |
| 1st Team | 2nd Team | Votes |