| Week | Add | Drop |
| Pre-Season |
Round 1: C Gary Sanchez - Mil | |
| Week 2 |
Round 1: OF Joey Gallo - Was Round 2: SP Javier Assad - ChN | |
| Week 3 |
Round 1: OF Sal Frelick - Mil Round 2: C Elias Diaz - Col |
Round 1: SP Kyle Hendricks - ChN Round 2: OF Jarred Kelenic - Atl |
| Week 4 |
Round 1: RP Kirby Yates - Tex |
Round 1: OF Joey Gallo - Was |
| Week 5 |
Round 1: 3B Orelvis Martinez - Tor Round 2: OF Jo Adell - LAA |
Round 1: SP Matt Manning - Det Round 2: RP Yuki Matsui - SD |
| Week 6 |
Round 1: SP Keaton Winn - SF Round 2: 2B Rob Refsnyder - Bos |
Round 1: OF Chas McCormick - Hou Round 2: RP Griffin Jax - Min |
| Week 7 |
Round 1: 3B Joey Ortiz - Mil |
Round 1: OF Sal Frelick - Mil |
| 1st Team | 2nd Team |
| Week 7 | |
| Indianapolis ABCs | The Shogun of Harlem |
|
OF
Jazz Chisholm
Mia |
OF
Jordan Walker
StL 1B Christian Encarnacion-Strand Cin |