| Week | Add | Drop |
| Pre-Season |
Round 1: 3B Zach Dezenzo - Hou Round 2: SP Brayan Bello - Bos Round 3: OF Mike Yastrzemski - SF Round A: SP Shane Bieber - Cle |
Round 3: OF Jerar Encarnación - SF |
| Week 1 |
Round 1: OF Alek Thomas - Ari Round 3: SP Drew Rasmussen - TB |
Round 3: 3B Zach Dezenzo - Hou |
| Week 2 |
Round 1: OF Mickey Moniak - Col Round 2: SP Germán Márquez - Col Round 3: 2B Zach McKinstry - Det |
Round 2: OF Andy Pages - LAD |
| Week 3 |
Round 1: 3B Chase Meidroth - ChA Round 2: SP Mike Lorenzen - KC Round 3: SP Jose Quintana - Mil |
Round 1: SP Carlos Carrasco - NYA Round 2: SP Miles Mikolas - StL Round 3: SP AJ Smith-Shawver - Atl |
| Week 4 |
Round 1: OF Austin Hays - Cin Round 2: OF Tim Tawa - Ari Round 3: C Drake Baldwin - Atl |
Round 1: OF Lane Thomas - Cle Round 2: SP Germán Márquez - Col Round 3: SP Tanner Houck - Bos |
| Week 5 |
Round 1: RP Camilo Doval - SF Round 2: 3B Zach Dezenzo - Hou |
Round 2: OF Alek Thomas - Ari |
| Week 6 |
Round 1: SP Luis Ortiz - Cle |
Round 1: 3B Zach Dezenzo - Hou |
| 1st Team | 2nd Team |
| Pre-Season | |
| Durham Bulls | Pollock's Cuban Stars |
|
RP
Josh Hader
Hou |
Round 4, 2nd Pick (RP Ryan Walker SF) |
| Pre-Season | |
| Durham Bulls | Chattanooga Lookouts |
|
SS
Anthony Volpe
NYA |
Round 5, 4th Pick (OF Kerry Carpenter Det) |