| Week | Add | Drop |
| Pre-Season |
Round 2: SP JP Sears - Oak Round A: SP Shane Baz - TB |
Round A: 2B Adam Frazier - KC |
| Week 1 |
Round 1: 2B Brice Turang - Mil Round 2: SP Colin Rea - Mil |
Round 2: SP JP Sears - Oak |
| Week 2 |
Round 1: 1B Garrett Cooper - Bos Round 2: OF Brandon Marsh - Phi |
Round 1: OF James Outman - LAD Round 2: RP Tanner Scott - Mia |
| Week 3 |
Round 1: OF Blake Perkins - Mil Round 2: OF Brenton Doyle - Col |
Round 1: OF Kerry Carpenter - Det |
| Week 4 |
Round 1: SS Amed Rosario - TB |
Round 1: SS Zach Neto - LAA |
| Week 5 |
Round 1: OF Mark Canha - Det |
Round 1: RP Adbert Alzolay - ChN |
| Week 6 |
Round 1: SP Spencer Turnbull - Phi |
Round 1: 1B Garrett Cooper - ChN |
| 1st Team | 2nd Team |
| Pre-Season | |
| Ft Myers Bull Sharks | Marlins |
|
Round 8, 5th Pick (C Henry Davis Pit) |
SP
Zach Eflin
TB |
| Pre-Season | |
| Ft Myers Bull Sharks | Bleacher Bums |
|
Round 1, 11th Pick (SP Logan Gilbert Sea) |
SP
Kevin Gausman
Tor |
| Pre-Season | |
| Ft Myers Bull Sharks | Hilldale of Darby |
|
C
Tom Murphy
SF OF Brent Rooker Oak |
Round 1, 12th Pick (3B Isaac Paredes TB) Round 2, 12th Pick (RP Alexis Diaz Cin) |
| Pre-Season | |
| Ft Myers Bull Sharks | San Diego Tigers |
|
SP
Drew Smyly
ChN |
Round 2, 1st Pick (SP Chris Sale Atl) |
| Pre-Season | |
| Ft Myers Bull Sharks | Dream Machine |
|
SP
Tommy Henry
Ari RP Felix Bautista Bal |
Round 1, 11th Pick (SP Logan Gilbert Sea) Round 4, 11th Pick (RP Adbert Alzolay ChN) |
| Pre-Season | |
| Ft Myers Bull Sharks | PHILLIE PRIDE |
|
Round 5, 5th Pick (3B Ryan McMahon Col) |
2B
Jeff McNeil
NYN |
| Pre-Season | |
| Ft Myers Bull Sharks | PHILLIE PRIDE |
|
Round 9, 5th Pick (SP Eduardo Rodriguez Ari) |
Round 10, 4th Pick (1B Jose Abreu Hou) Round 12, 4th Pick (SP Nick Pivetta Bos) Round 13, 4th Pick (SS Zach Neto LAA) |
| Pre-Season | |
| Ft Myers Bull Sharks | Marlins |
|
Round 2, 1st Pick (SP Chris Sale Atl) Round 2, 5th Pick (SP Carlos Rodon NYA) |
2B
Matt McLain
Cin Round 17, 8th Pick (2B Luis Rengifo LAA) Round 18, 8th Pick (OF Steven Kwan Cle) Round 19, 8th Pick |
| Pre-Season | |
| Ft Myers Bull Sharks | PHILLIE PRIDE |
|
SP
Aaron Nola
Phi |
Round 3, 3rd Pick (OF Ian Happ ChN) Round 7, 4th Pick (RP Tanner Scott Mia) |
| Pre-Season | |
| Ft Myers Bull Sharks | Bleacher Bums |
|
Round 4, 5th Pick (2B Xander Bogaerts SD) |
2B
Mike Moustakas
F/A |
| Pre-Season | |
| Ft Myers Bull Sharks | Ephesians |
|
Round 6, 5th Pick (SS Trevor Story Bos) |
SP
Cole Ragans
KC |
| Pre-Season | |
| Ft Myers Bull Sharks | Bleacher Bums |
|
Round 10, 4th Pick (1B Jose Abreu Hou) |
3B
Ke'Bryan Hayes
Pit |
| Pre-Season | |
| Ft Myers Bull Sharks | Marlins |
|
RP
Edwin Diaz
NYN |
1B
Nate Lowe
Tex Round 6, 3rd Pick (RP Craig Kimbrel Bal) |
| Pre-Season | |
| Ft Myers Bull Sharks | Dream Machine |
|
Round 1, 5th Pick (RP Raisel Iglesias Atl) Round 7, 5th Pick (2B Brandon Lowe TB) Round 1, 12th Pick (3B Isaac Paredes TB) |
OF
Randy Arozarena
TB SP Zac Gallen Ari |