| Week | Add | Drop |
| Pre-Season |
Round 1: C Gary Sanchez - Mil Round 2: OF Mickey Moniak - LAA | |
| Week 1 |
Round 1: SP Jordan Hicks - SF Round 2: RP Jason Foley - Det | |
| Week 2 |
Round 1: 1B Alex Kirilloff - Min Round 2: SP Cody Bradford - Tex | |
| Week 3 |
Round 1: SP Dean Kremer - Bal Round 2: 2B Jeff McNeil - NYN |
Round 2: OF Mickey Moniak - LAA |
| Week 4 |
Round 1: SP Jameson Taillon - ChN |
Round 1: 1B Kris Bryant - Col |
| Week 5 |
Round 1: RP Hector Neris - ChN Round 2: SP Emerson Hancock - Sea |
Round 1: 3B Luis Urias - Sea Round 2: SP Dean Kremer - Bal |
| Week 6 |
Round 1: OF Wenceel Perez - Det Round 2: C Connor Wong - Bos |
Round 1: SP Michael Wacha - KC Round 2: C Gary Sanchez - Mil |
| 1st Team | 2nd Team |
| Pre-Season | |
| bottom of the pack 20 | Cuban Stars |
|
Round 2, 11th Pick (SP Joe Musgrove SD) |
1B
Brandon Belt
F/A |
| Pre-Season | |
| bottom of the pack 20 | In Memory of Joe Fig |
|
Round 3, 11th Pick (C Cal Raleigh Sea) |
RP
Jason Adam
TB |
| Week 4 | |
| bottom of the pack 20 | Horseheads Buffalos |
|
SP
Kyle Hendricks
ChN 2B Jeff McNeil NYN OF Corbin Carroll Ari RP Jason Foley Det |
OF
Teoscar Hernández
LAD SP Dylan Cease SD 1B Spencer Torkelson Det 2B Jordan Westburg Bal |
| Week 6 | |
| bottom of the pack 20 | Savannah Sand Gnats |
|
1B
Spencer Torkelson
Det |
OF
Jarren Duran
Bos |