| Week | Add | Drop |
| Week 1 |
Round 1: OF Kosuke Fukudome - ChN | |
| Week 2 |
Round 1: SP Zach Duke - Pit | |
| Week 4 |
Round 2: OF Jose Guillen - KC | |
| Week 5 |
Round 1: OF Jose Guillen - KC Round 2: SP Jonathon Niese - NYN |
Round 1: RP George Sherrill - LAD Round 2: OF Chris Young - Ari |
| Week 6 |
Round 2: 3B Kevin Kouzmanoff - SD | |
| Week 7 |
Round 2: SS Adam Everett - Det |
Round 2: SP Jonathon Niese - NYN |
| Week 8 |
Round 1: SP Barry Zito - SF Round 2: SP Livan Hernandez - NYN |
Round 1: SP Armando Galarraga - Det Round 2: SP Jesse Litsch - Tor |
| Week 9 |
Round 2: 2B Akinori Iwamura - Pit |
Round 2: OF Xavier Nady - ChN |
| Week 10 |
Round 1: 3B Emilio Bonifacio - Fla Round 2: RP Rafael Soriano - Atl |
Round 1: 2B Akinori Iwamura - Pit Round 2: C Kelly Shoppach - Cle |
| Week 11 |
Round 2: SP Scott Richmond - Tor |
Round 2: RP Rafael Soriano - TB |
| Week 17 |
Round 2: SP Brett Myers - Hou |
Round 2: OF Jose Guillen - KC |
| Week 19 |
Round 2: SP Bobby Parnell - NYN |
Round 2: SP Scott Richmond - Tor |
| 1st Team | 2nd Team | Votes |
| Week 6 | ||
| Goombah | Great Lakes Loons | Decision |
|
3B
Miguel Tejada
Hou OF Magglio Ordonez Det SP Tim Lincecum SF |
OF
Xavier Nady
ChN SS Jose Reyes NYN OF Brad Hawpe Col |
Approved 20-3. See Breakdown |