| Week | Add | Drop |
| Pre-Season |
Round 1: SS J.P. Crawford - Sea Round 2: SP Charlie Morton - Bal | |
| Week 1 |
Round 1: C Bo Naylor - Cle Round 3: 3B Ernie Clement - Tor |
Round 3: SP Charlie Morton - Bal |
| Week 2 |
Round 1: 3B Dylan Moore - Sea Round 2: C Dillon Dingler - Det |
Round 1: 3B Ernie Clement - Tor Round 2: C Bo Naylor - Cle |
| Week 3 |
Round 2: SS Jose Caballero - TB |
Round 2: 3B Brett Baty - NYN |
| Week 4 |
Round 1: 1B Ryan O'Hearn - Bal Round 2: SP JP Sears - Oak Round 3: SP Lance McCullers - Hou |
Round 1: SS J.P. Crawford - Sea Round 2: SP Jake Irvin - Was Round 3: 1B Andrew Vaughn - ChA |
| Week 5 |
Round 2: OF Ceddanne Rafaela - Bos |
Round 2: OF Jo Adell - LAA |
| Week 6 |
Round 2: SP José Soriano - LAA |
| 1st Team | 2nd Team |
| Pre-Season | |
| Got Heeeem | Enter Sandman |
|
Round 5, 2nd Pick (SS Xavier Edwards Mia) |
3B
Josh Jung
Tex |
| Pre-Season | |
| Got Heeeem | Horseheads Buffalos |
|
SS
CJ Abrams
Was Round 1, 8th Pick (OF Tyler O'Neill Bal) Round 4, 8th Pick (C Yainer Diaz Hou) |
SP
Gerrit Cole
NYA OF Riley Greene Det Round 18, 9th Pick (3B Brett Baty NYN) Round 19, 9th Pick (OF Jung Hoo Lee SF) |
| Pre-Season | |
| Got Heeeem | Lakeland Flying Tigers |
|
OF
Byron Buxton
Min SP Bryce Miller Sea |
Round 5, 2nd Pick (SS Xavier Edwards Mia) Round 7, 2nd Pick (SP Carlos Rodon NYA) |
| Pre-Season | |
| Got Heeeem | The Shogun of Harlem |
|
Round 12, 8th Pick (2B Thairo Estrada Col) |
Round 16, 10th Pick (SP Chris Bassitt Tor) Round 17, 10th Pick (SP Jake Irvin Was) Round 18, 10th Pick (SP Bowden Francis Tor) Round 19, 10th Pick |