| Week | Add | Drop |
| Week 2 |
Round 1: SP Sean Manaea - NYN Round 2: OF Nick Martini - Cin |
Round 1: SP Eury Perez - Mia |
| Week 3 |
Round 1: SP Colin Rea - Mil Round 2: OF Brandon Marsh - Phi |
Round 2: 1B Kris Bryant - Col |
| Week 4 |
Round 1: SP José Butto - NYN Round 2: SP Clarke Schmidt - NYA |
Round 2: C Keibert Ruiz - Was |
| Week 5 |
Round 1: OF Pete Crow-Armstrong - ChN Round 2: OF Blake Perkins - Mil |
Round 1: SP J.P. France - Hou Round 2: OF Nick Martini - Cin |
| Week 6 |
Round 1: 1B Tyler Nevin - Oak Round 2: SP Cody Bradford - Tex |
Round 1: 3B Jared Triolo - Pit Round 2: RP Michael Kopech - ChA |
| 1st Team | 2nd Team |
| Week 3 | |
| I Didn’t Hear No Bell | Colorado Springs Snow Sox |
|
SP
Zach Wheeler
Phi C J.T. Realmuto Phi SP Matt Manning Det |
RP
Michael Kopech
ChA 2B Brice Turang Mil RP Camilo Doval SF |