| Week | Add | Drop |
| Pre-Season |
Round A: SS Colson Montgomery - ChA |
Round A: 1B Garrett Cooper - Bos |
| Week 1 |
Round 1: C Travis d'Arnaud - Atl Round 2: 3B Jared Triolo - Pit | |
| Week 2 |
Round 1: 1B Alex Kirilloff - Min Round 2: SP Javier Assad - ChN |
Round 2: 3B D.J. LeMahieu - NYA |
| Week 3 |
Round 1: SP Reynaldo Lopez - Atl |
Round 1: 3B Jared Triolo - Pit |
| Week 4 |
Round 1: SS Gabriel Arias - Cle Round 2: OF Esteury Ruiz - Oak |
Round 1: SP Bryce Elder - Atl Round 2: RP Will Smith - KC |
| Week 5 |
Round 1: SP Emerson Hancock - Sea Round 2: RP Garrett Cleavinger - TB |
Round 1: 1B Jose Abreu - Hou Round 2: OF Esteury Ruiz - Oak |
| Week 6 |
Round 1: SP Graham Ashcraft - Cin Round 2: C Danny Jansen - Tor |
Round 1: SP Logan Allen - Cle Round 2: RP Garrett Cleavinger - TB |
| Week 7 |
Round 1: C Tyler Soderstrom - Oak Round 2: RP Peter Fairbanks - TB |
Round 1: C Travis d'Arnaud - Atl Round 2: SP Emerson Hancock - Sea |
| Week 8 |
Round 1: 3B Joey Ortiz - Mil |
Round 1: SP Ben Brown - ChN |
| 1st Team | 2nd Team |
| Pre-Season | |
| Bleacher Bums | Ft Myers Bull Sharks |
|
SP
Kevin Gausman
Tor |
Round 1, 11th Pick (SP Logan Gilbert Sea) |
| Pre-Season | |
| Bleacher Bums | Ft Myers Bull Sharks |
|
2B
Mike Moustakas
F/A |
Round 4, 5th Pick (2B Xander Bogaerts SD) |
| Pre-Season | |
| Bleacher Bums | PHILLIE PRIDE |
|
Round 3, 10th Pick (RP Ryan Helsley StL) |
1B
Garrett Cooper
Bos |
| Pre-Season | |
| Bleacher Bums | Ft Myers Bull Sharks |
|
3B
Ke'Bryan Hayes
Pit |
Round 10, 4th Pick (1B Jose Abreu Hou) |
| Week 6 | |
| Bleacher Bums | San Diego Tigers |
|
SS
Gabriel Arias
Cle OF Jarren Duran Bos |
SP
Luis Castillo
Sea OF Lars Nootbaar StL |