| Week | Add | Drop |
| Pre-Season |
Round 1: RP Brian Wilson - SF | |
| Week 2 |
Round 1: OF Eric Hinske - TB |
Round 1: SS Eugenio Velez - SF |
| Week 3 |
Round 1: SP Jeff Niemann - TB Round 2: SP Greg Smith - Oak |
Round 1: OF Eric Hinske - Pit Round 2: OF Aaron Rowand - SF |
| Week 4 |
Round 1: SP Armando Galarraga - Det Round 2: SP Andy Sonnanstine - TB |
Round 1: 2B Akinori Iwamura - TB Round 2: 3B Melvin Mora - Bal |
| Week 5 |
Round 1: C Paul Bako - Cin | |
| Week 6 |
Round 1: SP Tommy Hanson - Atl Round 2: SP Wandy Rodriguez - Hou |
Round 1: SP Franklin Morales - Col Round 2: SP Rich Hill - Bal |
| Week 9 |
Round 1: OF Jerry Hairston Jr. - Cin |
Round 1: SP Ubaldo Jimenez - Col |
| Week 10 |
Round 1: SP Josh Banks - SD |
Round 1: RP Jonathan Broxton - LAD Round 2: C Paul Bako - ChN |
| Week 11 |
Round 1: OF Brian Horwitz - SF |
Round 1: OF Jerry Hairston Jr. - Tex |
| 1st Team | 2nd Team | Votes |
| Pre-Season | ||
| Seventh Inning Stretch | SPITBALLERS | Decision |
|
1B
Lance Berkman
Hou RP Jose Valverde Hou OF Melvin Upton TB |
1B
Carlos Guillen
Det SP Erik Bedard Sea SP Rich Hill Bal 1B James Loney LAD |
Approved 20-3. See Breakdown |
| Week 3 | ||
| Seventh Inning Stretch | Cincinnati Tigers | Decision |
|
3B
Troy Glaus
StL SP Dustin McGowan Tor SP Roberto Hernandez Cle |
3B
Evan Longoria
TB OF Jay Bruce Cin |
Approved 14-4. See Breakdown |
| Week 3 | ||
| Seventh Inning Stretch | SPITBALLERS | Decision |
|
SP
Aaron Harang
Cin |
1B
Billy Butler
KC SP Joba Chamberlain NYA |
Approved 17-1. See Breakdown |
| Week 13 | ||
| Seventh Inning Stretch | SPITBALLERS | Decision |
|
SP
Joba Chamberlain
NYA |
SS
Troy Tulowitzki
Col |
Approved 15-0. See Breakdown |
| Week 14 | ||
| Seventh Inning Stretch | Flying Elvises | Decision |
|
OF
Brad Hawpe
Col SP Wandy Rodriguez Hou |
SP
Chad Billingsley
LAD |
Approved 16-2. See Breakdown |