| Week | Add | Drop |
| Pre-Season |
Round A: OF Kosuke Fukudome - ChN |
Round A: 1B Kevin Millar - Bal |
| Week 1 |
Round 1: SP Livan Hernandez - Col Round 2: SP Carlos Villanueva - Mil |
Round 2: OF Brandon Moss - Pit |
| Week 2 |
Round 1: SP Jeff Suppan - Mil Round 2: 3B Brandon Inge - Det |
Round 1: C Ronny Paulino - Pit |
| Week 5 |
Round 1: SP Armando Galarraga - Det |
Round 1: DH Frank Thomas - Oak Round 2: SP Franklin Morales - Col |
| Week 6 |
Round 1: SP Darrell Rasner - NYA |
Round 1: SP Jeff Suppan - Mil |
| Week 7 |
Round 2: OF Gary Matthews Jr. - LAA |
Round 2: OF Lastings Milledge - Was |
| Week 8 |
Round 1: C Jesus Flores - Was |
Round 1: SP Carlos Villanueva - Mil |
| Week 9 |
Round 1: 2B Alexi Casilla - Min |
Round 1: 3B Brandon Inge - Det |
| Week 10 |
Round 1: OF Carlos Gonzalez - OAK Round 2: SP Josh Banks - SD | |
| Week 11 |
Round 1: OF Matt LaPorta - Cle |
Round 1: SP Oliver Perez - NYN |
| Week 12 |
Round 1: OF Brandon Jones - Atl |
Round 1: OF Gary Matthews Jr. - LAA |
| Week 13 |
Round 1: OF Cameron Maybin - Fla Round 2: OF Rocco Baldelli - TB |
Round 1: 1B Nomar Garciaparra - LAD Round 2: OF Brandon Jones - Atl |
| Week 18 |
Round 1: SP Jeff Samardzija - ChN |
Round 1: SP Garrett Olson - Sea |
| 1st Team | 2nd Team | Votes |