| Week | Add | Drop |
| Pre-Season |
Round 2: SP Kyle Gibson - StL Round A: 1B Joey Votto - Tor |
Round A: SP Rich Hill - F/A |
| Week 1 |
Round 2: SP Sean Manaea - NYN | |
| Week 2 |
Round 1: SP Steven Matz - StL | |
| Week 5 |
Round 1: OF Jake Fraley - Cin Round 2: OF Mark Canha - Det |
Round 1: 2B Brandon Drury - LAA Round 2: 1B Jose Abreu - Hou |
| Week 6 |
Round 1: SP Trevor Williams - Was |
Round 1: SP Steven Matz - StL |
| 1st Team | 2nd Team |
| Pre-Season | |
| Cardinals | Dave's Destroyers |
|
OF
Byron Buxton
Min Round 15, 1st Pick (SP Brandon Pfaadt Ari) |
1B
Nate Lowe
Tex Round 7, 5th Pick (SP Jose Berrios Tor) Round 19, 5th Pick |
| Week 2 | |
| Cardinals | Red Dragon |
|
SP
Kyle Gibson
StL |
2B
Brendan Donovan
StL |