| Week | Add | Drop |
| Pre-Season |
Round A: OF Garrett Mitchell - Mil Round B: SP Cristian Javier - Hou | |
| Week 1 |
Round 1: SP Jack Leiter - Tex Round 2: 3B Yoan Moncada - LAA Round 3: SP Jordan Hicks - SF | |
| Week 2 |
Round 1: SS Kyren Paris - LAA Round 2: SP Chase Dollander - Col |
Round 1: SP Hayden Birdsong - SF Round 2: SP Simeon Woods Richardson - Min |
| Week 3 |
Round 1: 2B Brendan Rodgers - Hou Round 2: 1B Joshua Bell - Was Round 3: SP Richard Fitts - Bos |
Round 1: OF Daulton Varsho - Tor Round 2: 2B Tyler Fitzgerald - SF Round 3: 1B Willson Contreras - StL |
| Week 4 |
Round 1: 3B Sal Stewart - Cin Round 2: SP Logan Allen - Cle Round 3: SP Landen Roupp - SF |
Round 1: 3B Yoan Moncada - LAA Round 2: 1B Joshua Bell - Was Round 3: SP Chase Dollander - Col |
| Week 5 |
Round 1: RP Cade Smith - Cle Round 2: OF Andrew McCutchen - Pit Round 3: 1B Michael Toglia - Col |
Round 1: OF Garrett Mitchell - Mil Round 2: SP Jordan Hicks - SF Round 3: 3B Sal Stewart - Cin |
| Week 6 |
Round 1: RP David Bednar - Pit Round 2: SP Chase Burns - Cin |
Round 1: SP Logan Allen - Cle Round 2: RP Ryan Walker - SF |
| 1st Team | 2nd Team |