| Week | Add | Drop |
| Pre-Season |
Round 1: 2B Darwin Barney  Round 2: 3B Jeff Keppinger  | |
| Week 2 |
Round 1: RP Jim Henderson  Round 2: SP Chris Capuano  |
Round 1: 3B Jeff Keppinger Round 2: 2B Jemile Weeks  |
| Week 3 |
Round 1: RP Wily Peralta |
Round 1: OF Michael Brantley  |
| Week 5 |
Round 1: SP Shaun Marcum  |
Round 1: SP Chris Capuano |
| Week 6 |
Round 2: SP Hiram Burgos |
Round 2: SP Shaun Marcum |
| Week 11 |
Round 1: SP Rick Porcello  |
Round 1: SP Hiram Burgos |
| Week 13 |
Round 2: SP Johnny Hellweg |
Round 2: SP Michael Fiers |
| Week 17 |
Round 1: OF Caleb Gindl |
Round 1: SP Clayton Richard  |
| Week 19 |
Round 2: SS Jeff Bianchi |
Round 2: OF Peter Bourjos  |
| 1st Team | 2nd Team | Votes |
| Week 13 | ||
| Churchills | Hillsboro Hops | Decision |
|
OF
Carlos Beltran
|
SP
Hiroki Kuroda
 |
Approved 12-0. See Breakdown |