| Week | Add | Drop |
| Pre-Season |
Round A: OF Jacoby Ellsbury - Bos |
Round A: OF Reggie Willits - LAA |
| Week 1 |
Round 1: SP Jeff Suppan - Mil Round 2: SS Brian Bocock - SF | |
| Week 2 |
Round 1: SP Justin Germano - SD Round 2: 3B Ty Wigginton - Hou |
Round 1: SS Jason Bartlett - TB Round 2: 1B Willy Aybar - TB |
| Week 3 |
Round 1: OF Jason Kubel - Min Round 2: OF Eric Hinske - TB |
Round 1: OF Jack Cust - Oak Round 2: 3B Scott Rolen - Tor |
| Week 4 |
Round 1: 1B Nomar Garciaparra - LAD Round 2: SP Armando Galarraga - Det |
Round 1: SS Brian Bocock - SF Round 2: 3B Ty Wigginton - Bal |
| Week 5 |
Round 1: SP Andy Sonnanstine - TB Round 2: SS Erick Aybar - LAA |
Round 1: 1B Nomar Garciaparra - LAD Round 2: SP Justin Germano - SD |
| Week 6 |
Round 1: SP Daniel Cabrera - Bal Round 2: C Miguel Olivo - KC |
Round 1: OF Jason Kubel - Min Round 2: C Ronny Paulino - Pit |
| Week 7 |
Round 1: C Brian Schneider - NYN Round 2: SP Nick Blackburn - Min |
Round 1: C Miguel Olivo - Fla Round 2: SP Jeff Suppan - Mil |
| Week 8 |
Round 1: OF Matt Joyce - Det Round 2: 2B Marcos Scutaro - Tor |
Round 1: SS Erick Aybar - LAA Round 2: SP Kyle Kendrick - Phi |
| Week 9 |
Round 1: SP Bryan Bullington - Pit Round 2: RP Dana Eveland - Oak |
Round 1: 1B Lyle Overbay - Tor Round 2: RP Todd Jones - Det |
| Week 10 |
Round 1: 1B Lyle Overbay - Tor Round 2: SS Alexei Ramirez - ChA |
Round 1: SP Bryan Bullington - Pit Round 2: C Brian Schneider - NYN |
| Week 11 |
Round 1: SP Jamie Moyer - Phi |
Round 1: OF Matt Joyce - Det |
| Week 12 |
Round 1: SP Todd Wellemeyer - StL Round 2: OF Jason Kubel - Min |
Round 1: DH Frank Thomas - Oak Round 2: SP Jamie Moyer - Phi |
| Week 13 |
Round 1: OF Jim Edmonds - ChN Round 2: C Jesus Flores - Was |
Round 1: SP Daniel Cabrera - Bal Round 2: 1B Adam LaRoche - Pit |
| Week 14 |
Round 1: OF Jerry Hairston Jr. - Cin Round 2: OF Adam Jones - Bal |
Round 1: 2B Marcos Scutaro - Tor Round 2: C Jesus Flores - Was |
| Week 15 |
Round 1: SS Ramon Vazquez - Tex Round 2: SP Dave Bush - Mil |
Round 2: SP Kelvim Escobar - LAA |
| Week 17 |
Round 1: C Jesus Flores - Was Round 2: SP Randy Johnson - Ari |
Round 1: OF Jerry Hairston Jr. - Tex Round 2: SP Dave Bush - Mil |
| Week 18 |
Round 1: C John Buck - KC |
Round 1: SP Dustin McGowan - Tor |
| Week 19 |
Round 2: SS Ramon Vazquez - Tex |
| 1st Team | 2nd Team | Votes |
| Week 4 | ||
| Jersey Thunder | Mets | Decision |
|
OF
Jacoby Ellsbury
Bos |
SS
Yunel Escobar
Atl |
Approved 18-0. See Breakdown |
| Week 4 | ||
| Jersey Thunder | Dookie | Decision |
|
DH
Jose Vidro
Sea 3B Aramis Ramirez ChN SS Julio Lugo Bos |
3B
Mike Lowell
Bos SS Troy Tulowitzki Col 3B Kevin Kouzmanoff SD |
Approved 16-2. See Breakdown |
| Week 13 | ||
| Jersey Thunder | Dookie | Decision |
|
OF
Torii Hunter
LAA RP Jose Valverde Hou SP Philip Hughes NYA SP Andy Sonnanstine TB |
SP
Erik Bedard
Sea SP Dustin McGowan Tor OF Kosuke Fukudome ChN SP Johnny Cueto Cin |
Approved 14-2. See Breakdown |
| Week 13 | ||
| Jersey Thunder | Warhammer | Decision |
|
OF
Adam Dunn
Cin SS Troy Tulowitzki Col |
OF
Vernon Wells
Tor SP Cliff Lee Cle |
Approved 15-1. See Breakdown |